In the 1800s, thousands of members of the Cherokee Nation were displaced from their homes and traditional territories. The separation of the Cherokee from their homes and homelands along with the subsequent destruction of their homes during their forced removal in the late 1830s, was one of the most widespread campaigns of domicide to take place within the borders of the United States. By uprooting an entire Indigenous population and forcibly displacing them to land west of the Mississippi, the government of the United States created space for white settlers in former Cherokee territories. This case is particularly illuminating for understanding the pervasive effects of bureaucratic violence on targeted Indigenous communities.